The popular period drama Masters of Sex is now available to stream on Prime Video, making it an ideal choice for a weekend binge-watching session.

Based on Thomas Maier's biography of the same name, the show follows the story of William Masters, a fertility specialist played by Michael Sheen, who embarks on a groundbreaking study of human sexuality.

He is joined by his new secretary, Virginia Johnson (Lizzy Caplan), and together they conduct their research in secret, observing human behavior during intimate moments.

The series, which initially aired from 2013 to 2016, received widespread critical acclaim and was even nominated for a Golden Globe Award for Best Drama.

The show boasts an impressive cast, including Caitlin FitzGerald, Teddy Sears, Nicholas D'Agosto, and Annaleigh Ashford, with notable guest appearances by Beau Bridges, Sarah Silverman, and Jeremy Strong.

Reviews for Masters of Sex have been overwhelmingly positive, with The Hollywood Reporter praising the show for its thought-provoking approach.

The publication wrote in its review: "Masters of Sex manages, with lightning speed, to shed any preconceived notions about what type of show it will be and, in so doing, tilts the camera up from the breast to the brain."

The Denver Post has lauded Masters of Sex as an "The engrossing, beautifully cast and well-acted Masters of Sex is at once the tale of an odd couple and the story of a culture coming of age."

Viewers have hailed it as the "best series ever", showering praise on its storylines and performances, reports SurreyLive.

One fan wrote online: "The best series ever! So dramatic, so interesting... There is no fantasy and mystics in it, but the characters here are thousand times better than all fantastic and magical world's elements like in many other shows.

"The storyline is amazing, screenplay is just perfect."

Another viewer praised: "Absolutely brilliant first two seasons. Story, script, acting, period production, cinematography, editing. Terrific. One of the ten best television series ever made," with another agreeing: "One of the BEST series I have ever watched."

Masters of Sex is streaming on Amazon Prime Video.